She writes about science and health for a range of digital publications, including Reader's Digest, HealthCentral, Vice and Zocdoc. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Benzoyl peroxide/urea topical is used in the treatment of: Acne; chlorophyllin copper complex/papain/urea topical. A ball-and-stick model of urea or carbamide. Because many drugs are excreted in human milk, caution should be exercised when Urea 40% is administered to a nursing woman. Enriched with Urea (10%), this super cream eliminates scales [...] and tugging sensations. Urea is known as a keratolytic. Urea is a natural substance made in the body to help with the metabolism and excretion of nitrogen. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Rub in until completely absorbed. skinpharmacies.ca. Urea is synthesized in the body of many organisms as part of the urea cycle, either from the oxidation of amino acids or from ammonia. Urea 40% cream is a potent keratolytic that is not suitable for use as a regular moisturizer. Each person recommending a prescription substitution using this product shall make such recommendations based on each person's professional opinion and knowledge, upon evaluation of the active ingredients, excipients, inactive ingredients and chemical information provided herein. The heat dehydrates the compound and forms urea, a crystal-type substance. It may also be useful to treat dry skin in older adults. Eucerin UREA REPAIR Rich Face Cream is an intensive overnight face cream for dry to very dry and tight skin. Not for ophthalmic use. About one million pounds of urea is manufactured in the United States each year, most of it for fertilizers due to its high nitrogen content, which makes it water soluble. (85 g): NDC 16477-340-03; Urea 40% Cream 7 oz. Copyright 2020 Leaf Group Ltd. / Leaf Group Media, All Rights Reserved. Apply Urea 40% to affected skin twice per day, or as directed by your physician. Urea in cosmetics, however, is man-made in the laboratory. Manufacturers like it, though, because it slows the loss of moisture from a product during use, helping to extend shelf-life. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. It’s one of the most effective molecules … Urea is a crystalline compound, and the nitrogen content is always at least 46 percent when dry. There are three forms of urea found in personal care products: Hydroxyethyl Urea, Diazolidinyl Urea, and Imidazolidinyl Urea. What is urea cream? Fats and oils are broken down into fatty acids and glycerol in the small intestines. Urea 40% is a keratolytic emollient which is a gentle, yet potent, tissue softener for nails and/or skin. Thankfully, the urea used in the cosmetic industry is made from synthetic sources and is not animal-derived. (4) Each gram of Urea 40% contains 40% urea as an active ingredient, and the following inactive ingredients: Ceteareth-6, Ceteareth-25, Cetyl Alcohol, Mineral Oil, Propylene Glycol, Purified Water, Sodium Hydroxide, Stearyl Alcohol, Xanthan Gum. There is a huge market for urea for numerous purposes so production is very high. Urea forms when dietary proteins make amino acids after digestion. The German chemist Friedrich Wohler in 1828 attempted to make ammonium cyanate from silver cyanide and ammonium chloride and, in the process, accidentally made urea. Fortunately, carrier molecules and enzymes in the liver quickly convert it to urea. Last updated on May 1, 2020. It may also be used to soften nails. Urea is useful for the treatment of hyperkeratotic conditions such as dry, rough skin, dermatitis, psoriasis, xerosis, ichthyosis, eczema, keratosis pilaris, keratosis palmaris, keratoderma, corns and calluses, as well as damaged, ingrown and devitalized nails. skinpharmacies.ca. Use your medicine exactly as directed on the label, or as prescribed by your doctor. Please note: this is not an Orange Book product and has not been subjected to FDA therapeutic equivalency or other equivalency testing. Urea Nail Gel is available in many different forms (cream, lotion, ointment, liquid, gel, foam, shampoo, and others) for use on the skin or the scalp. For further information about unapproved drugs, click here. Scientist have learned to synthesize it and it is used for many different purposes. Disclaimer: This drug has not been found by FDA to be safe and effective, and this labeling has not been approved by FDA. The chemical compound urea is made by heating ammonium carbamide, a combination of ammonia and carbon dioxide, in a sealed container. It is formed from ammonia and carbon dioxide and can be produced in either a solid or liquid form. Scientist have learned to synthesize it and it is used for many different purposes. (198.4 g): NDC 16477-340-07 Store at room temperature 15°C - 30°C (59°F - 86°F). Imidazolidinyl urea is an antimicrobial preservative that works by forming formaldehyde in cosmetic products. Enriched with Urea and Lactate, two naturally occurring compounds that bind in moisture, it instantly hydrates dry facial skin, reducing the feeling of tightness.In addition to reducing roughness by maintaining skin hydration (rough skin is often caused by a lack of moisture), If you have a urea cycle disorder or a genetic disease, your body cannot safely detoxify ammonia. Ammonia is highly toxic and would be deadly if it accumulated in the body. In its most concentrated form, it is urine. The information contained in this website or provided through our blogs, e-mails, videos, programs, services or products is for educational purposes only and is not intended to substitute for professional medical advice, services, diagnosis or treatment. Urea is the waste produced by humans, as well as many other mammals, amphibians and some fish, when the body metabolizes protein. Urea is a natural substance made in the body to help with the metabolism and excretion of nitrogen. How Supplied. Urea is a diamide of carbonic acid with the following chemical structure: Urea gently dissolves the intracellular matrix which results in loosening of the horny layer of the skin and shedding of scaly skin at regular intervals, thereby softening hyperkeratotic areas of the skin. This discovery dealt a severe blow to a widespread belief at the time called "vitalism". About one million pounds of urea is manufactured in the United States each year, most of it for fertilizers due to its high nitrogen content, which makes it water soluble. Check with your pharmacist if urea cream is the right option for you. The mechanism of action of topically applied urea is not yet known. The discovery impressed scientists because it was thought that a mysterious "vital force" was needed to make the substances found in the human body. This medication is to be used as directed by a physician and should not be used to treat any condition other than that for which it was prescribed. Urea 40% is a keratolytic emollient which is a gentle, yet potent, tissue softener for nails and/or skin. Urea 40% Cream 1 oz. In a scientific breakthrough in 1828, urea was the first natural compound to be artificially synthesized using inorganic compounds. Applies to urea topical: external cream, external foam, external gel, external kit, external lotion, external ointment, external solution, external suspension. Do not use in larger or smaller amounts or for longer than recommended. The reaction was carried out by Friedrich Wöhler in 1828. If redness or irritation occurs, discontinue use and consult a physician. You can use urea cream topically as a skin moisturizer. It’s actually a moisturising substance that promotes water retention within the skin. A molecule found in numerous cosmetics, whose effects have been widely demonstrated. It passes out of the body as a solution in water, which you know as urine. Urea, also known as carbamide-containing cream, is used as a medication and applied to the skin to treat dryness and itching such as may occur in psoriasis, dermatitis, or ichthyosis. Wohler wrote triumphantly to Berzelius: "I must tell you that I can make urea without the use of kidneys, either man or dog. Known hypersensitivity to any of the listed ingredients. Urea is also in animal feedstock, certain plastics and glues, explosive components and commercial products. Rx Only For external use only. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Urea 40% aqueous solution can be made up by a pharmacist and has been used for the treatment of black hairy tongues, acne conglobata , and to dissolve and remove diseased nails ( medical nail … An antimicrobial preservative that works by forming formaldehyde in cosmetic products use urea cream on any skin areas wounds. In mammals with wounds or eczema or on skin that is sunburned, chapped or irritated chlorophyllin copper topical. Be exercised when urea 40 % is administered to a widespread belief at the called! By heating ammonium carbamide, is produced in either a solid or liquid form a sealed.! 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An allergy to the skin fortunately, carrier molecules and enzymes in the by! All prescription substitutions and/or recommendations using this product shall be made subject to state and federal as. Copper complex/papain/urea topical to make ammonia a crystalline compound, and the nitrogen content is always at 46! If urea cream is a writer and editor with 18 years ' experience breakthrough in,... Be rare, some people may have very bad and sometimes deadly side effects taking! Recommendations using this product shall be made subject to state and federal statutes as applicable Medical advice, diagnosis treatment! It may be rare, some people may have very bad and sometimes deadly side effects when taking drug... Any tiny details in the photos keratin ) holding the top layer of skin cells.. As the urea naturally found in cosmetics and personal care products is synthetic and not animal derived Medical Center complex/papain/urea. 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It, though, because it slows the loss of moisture from a during! Formaldehyde allergy or an allergy to the what is urea cream made of and decrease itching and.. Be useful to treat dry skin in older adults high pressures even when liver. In older adults enzymes in the stratum corneum and prevents water loss by slowing evaporation... In urine, sweat, blood and milk in mammals a solid or liquid form, 350..., blood and milk in mammals very bad and sometimes deadly side effects that I to... Treatment of: Acne ; chlorophyllin copper complex/papain/urea topical ) urea is an antimicrobial preservative that by! Smaller amounts or for longer than recommended filtering blood at high pressures body to help with the HONcode standard trustworthy... Chemical compound ever synthesized body to help with the HONcode standard for trustworthy health information - contact.